Well, this is interesting.
Here’s an audio interface for the iPhone/iPad, which allows it to be put in the signal chain of a guitar, mic, synth…whatever. It’s made by New Signal Process, and is in the form of a stompbox and handles all the impedance matching necessary to send signals into, then out of the iPhone/iPad.
For guitarists, this means the ability to have a limitless supply of virtual and emulated effects that you can use for performances instead of just in the studio or sitting at a computer. It’s true bypass, and though the photo shows the standard version with a toggle switch, they will make them with a standard 3PDT switch as well if you ask. It costs a reasonable $115 and can be bought at the NSP site.
They don’t mention the iPhone/iPad version of Amplitude on the site , but it seems like it should work. They do say that latency can be an issue, and varies from app to app.
A lot of the samples on the site are using synths and vocals, but theres a few with guitar.
Here’s an audio sample running a guitar through the Moog Filtaron app.
And here’s a few videos. Not great quality but they help give an idea of how you might use something like this.